The risk of human breast cancer is concerned to cumulative exposure of the breast cells to endogenous estrogens. Strategies aiming at reducing the production of estrogens may be useful for the prevention of estrogens-related breast cancer. Several natural products with plant origin have the potential value as chemo-preventive or therapeutic agents in cancer. Flavonoids, the natural polyphenol c...

The risk of human breast cancer is concerned to cumulative exposure of the breast cells to endogenous estrogens. Strategies aiming at reducing the production of estrogens may be useful for the prevention of estrogens-related breast cancer. Several natural products with plant origin have the potential value as chemo-preventive or therapeutic agents in cancer. Flavonoids, the natural polyphenol c...

Umbelliprenin is a sesquiterpene coumarin with vitro anti-carcinogenic activities. The aim of this study was to investigate the antitumor effects of umbelliprenin in animal models of colorectal cancer. The cytotoxic effects of umbelliprenin were explored on CT26 and L929by MTT assay. In this study, colorectal tumors developed in mice by intradermal injection of CT26 cell line. Tumor size, serum...

Umbelliprenin is a sesquiterpene coumarin with vitro anti-carcinogenic activities. The aim of this study was to investigate the antitumor effects of umbelliprenin in animal models of colorectal cancer. The cytotoxic effects of umbelliprenin were explored on CT26 and L929by MTT assay. In this study, colorectal tumors developed in mice by intradermal injection of CT26 cell line. Tumor size, serum...

Phytochemicals show many desirable functions such as anti-oxidant, anti-microbial, anti-inflammatory, anti-carcinogenic, anti-ageing, activities and so on.These biological can only be seen when the compounds are delivered at sufficient concentrations. However, bioavailability of phytonutrients suffers from their limited absorption, transformation, rapid clearance circulation. In this review, we...

Conjugated linoleic acids (CLA) are distinctive polyunsaturated fatty acids. They present in food produced by ruminant animals and they accumulated seeds of certain plants. These naturally occurring substances have demonstrated to anti-carcinogenic activity. Their potential effect inhibit cancer has been shown vivo vitro studies. In this review, we the multiple effects CLA isomers on developmen...

Melatonin is a hormone that exhibits many bioactivities such as antioxidant, anti-inflammatory, anti-carcinogenic, anti-diabetic, neuroprotective, and anti-aging activity. In addition, melatonin has been used to strengthen the effect of drugs or agents for treatment in different disease models cancer, tumor, bacterial infection, autoimmune diseases, gastrointestinal diseases. According recent s...